Play it again: reactivation of waking experience and memory
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- Play it again: reactivation of waking experience and memory J. OāNeill, B. Pleydell-Bouverie, D. Dupret, J. Csicsvari 2010 š« 2023-02-28 reading citation Print:: ā
Zotero Link:: OāNeill et al_2010_Play it again.pdf; ScienceDirect Snapshot Zotero Link:: NA PDF:: NA Files:: OāNeill et al_2010_Play it again.pdf; ScienceDirect Snapshot Reading Note:: J. OāNeill, B. Pleydell-Bouverie, D. Dupret, J. Csicsvari (2010) Web Rip::
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Abstract
Episodic and spatial memories each involve the encoding of complex associations in hippocampal neuronal circuits. Such memory traces could be stabilised from short- to long-term forms by consolidation processes involving the āreactivationā of the original network firing patterns during sleep and rest. Waking experience can be replayed in many different brain areas, but an important role for the hippocampus lies in the organisation of the āreactivationā process. Emerging evidence suggests that sharp wave/ripple (SWR) events in the hippocampus could coordinate the reactivation of memory traces and direct their reinstatement in cortical circuits. Although the mechanisms remain uncertain, there is a growing consensus that such SWR-directed reactivation of brain-wide memory traces could underlie memory consolidation.
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